Therapeutic radionuclides include those emitting alpha particles, beta particles, or Auger electrons. Among them, alpha particles are characterized by high energy, strong focusing, short range, significant radiobiological effects, and potent cytotoxicity. After precise targeting of tumors, alpha radionuclides can release their enormous energy within the region of minimal residual disease, efficiently killing tumor cells while minimizing ionizing radiation damage to surrounding normal tissues and organs.
²¹¹At is the most promising alpha-emitting radionuclide for targeted therapy, and its application serves as the cornerstone and distinguishing feature of our technology platform.
• Clear Decay Chain
As an alpha emitter, ²¹¹At significantly improves therapeutic efficacy while reducing patients whole-body radiation dose and enhancing treatment safety— a distinct advantage over other alpha radionuclides (e.g., ²²⁵Ac, ²¹²Pb, etc.).
• Optimal Half-Life
With a half-life of 7.2 hours, ²¹¹At is well-suited for outpatient treatment, facilitating precision design of drug and clinical application.
• Ideal for Minimal Residual Disease
Its physical properties make it highly promising for eradicating post-surgical residual lesions, preventing recurrence, and treating micrometastases.
• Stable Supply Partnership
InnovaRadi has established strategic cooperation with leading global ²¹¹At manufacturers to ensure the stable supply of high-quality ²¹¹At.



Core of targeted radionuclide therapy lies in using molecular carriers with high specificity and affinity for tumor cells to deliver radionuclides precisely to target tumor tissues.
• Small Molecules
Optimized through structural design, featuring high specificity and favorable pharmacokinetic profiles.
• Single-Domain Antibodies (sdAbs)
Derived from alpaca immune screening, sdAbs offer advantages such as small molecular weight, high affinity, and strong tumor penetration, making them an ideal delivery platform for alpha radionuclides.

Our self-developed radionuclide-carrier conjugation platform enables efficient and stable radiolabeling, improving tumor retention and reducing off-target damage caused by radionuclide detachment. The platform features excellent modular compatibility, supporting the rapid development of multi-target and multi-radionuclide drugs as well as CMC process translation. 